PROTEOMICS SERVICES
 
Chemical Proteomics, Peptidomics, and Proteomics
DRUG SCREENING LIBRARY Probe+
 
A Probe for Every Protein
Drug Screening Active Compound Library
Phenols Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Phenols Active Compounds Library Probe+ LA-001 Active Compounds 265
M Series 472
C Series  623
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well

  Phenolic compounds mainly refer to a class of hydroxyl (-OH) or methoxy (-OMe) directly combined with aromatic base groups, which have strong antioxidant properties, antibacterial and enzyme properties, anti-tumor and other functions Natural products.

 

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Polyphenol Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Polyphenol Active Compounds Library Probe+ LA-002 Active Compounds 198
M Series 427
C Series  522
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well

  Polyphenol compounds mainly refer to a class of natural products composed of two or more hydroxyl groups (-OH) or methoxy groups (-OMe) directly combined with aromatic hydrocarbon groups. They are widely found in plants and have strong antioxidant properties. Antibacterial and enzyme-inhibiting properties, anti-tumor and other multifunctional natural products. The main structure includes flavonoids, quinones, alkaloids, phenylpropanoids and other polyphenols.

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Flavonoid Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Flavonoid Active Compounds Library Probe+ LA-003 Active Compounds 52
M Series 163
C Series  165
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well

  Flavonoids are widely found in plants in nature and belong to the secondary metabolites of plants. Flavonoids are a type of yellow pigment derived from flavonoids (2-phenylchromone) as the core. Flavonoids are widely present in plants and are natural products with strong antioxidant properties, antibacterial and enzyme properties, anti-tumor and other multi-functional natural products. 

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Jujube Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Jujube Active Compounds Library Probe+ LA-004 Active Compounds 27
M Series 76
C Series  113
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well

  Zizyphus jujuba dates (zizyphus jujuba dates) are the fruits of the jujube tree (zizyphus iujuba Mill) of the genus Rhamnaceae. Modern pharmacology has found that red dates contain a variety of active natural products, such as carbohydrates, vitamins, triterpenoids, cyclic adenosine phosphate and polyphenols.

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Salicylic Acid Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Salicylic Acid Active Compounds Library Probe+ LA-005 Active Compounds 17
M Series 25
C Series  48
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well

Salicylates (Salicylates) drugs include aspirin and sodium salicylate (Sodium Salicylate), etc., due to its strong irritation, salicylic acid itself is only used as an antifungal and keratolytic agent.  

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Anti-Cancer Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Anti-Cancer Active Compounds 
Library Probe+
LA-006 Active Compounds 139
M Series 201
C Series  295
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well

   In currently, Cancer one of the most common and most serious diseases that directly endanger human life. According to incomplete statistics, nearly 20 million people in the world suffer from cancer every year, and about 10 million people die from cancer, accounting for the total number of deaths. About 1/4, this number is still growing rapidly.

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Immunologically Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Immunologically Active Compounds Library Probe+ LA-008 Active Compounds 75
M series 131
C series 167
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well

  "Immunity" is an extremely important self-defense function of the human body. The human body can resist a huge variety of diseases by relying on its own immunity. Many active substances in natural products have immunological activity, such as polyphenols, flavonoids, and nitrogen-containing heterocyclic compounds.  

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Anti-Aging Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Anti-Aging Active Compounds Library Probe+ LA-009 Active Compounds 118 
M Series 230
C Series  274
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well
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Case Study

     

Baicalin is an active ingredient in a class of natural products. It has been found to reduce the accumulation of lipids in cells. In order to study its corresponding protein targets and biological activity mechanisms, the researchers designed probe molecules corresponding to its active ingredients and carried out chemistry. The identification of proteomics found that the protein target corresponding to baicalin was CPT1A, and through subsequent binding experiments, in vitro activity experiments, and animal phenotyping experiments, the mechanism of its CPT1A target was verified, and it was successful. The anti-obesity and anti-steatosis effects of baicalin depend on its interaction with CPT1A.

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AUTOMATION EQUIPMENT
 
Accelerate Drug Development
Scientific Research Automation Equipment and Development (ODM)
Keyone is a fully owned company of Leadart Technologies. Keyone is mainly engaged in the research and development, production, and sales of automated high-end equipment in the biomedical and biopharma field. Keyone has more than 38 patents and 28 software copyrights, and the commercially available products are listed here.Keyone is aspired to lead industry digitalization and automaton, free the hands of the researchers, providing automatic and intelligent solutions, and fill the gaps of automatic equipment needs. The company has customers from first-line research institutions, medical industry, health and beauty industries, scientific research institutions, medical institutions, pharmaceutical companies, biotechnology companies, third-party testing platforms and other customers.Free the hands of biologists and chemists.
 

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