• LeadArt Technologies provides closed-loop services from active compounds to target identification
• Probe synthesis and target identification are customized service items of chemical proteomics
Peptide group refers to all endogenous polypeptides in biological tissues or body fluids, including signal molecules (such as cytokines, growth factors, and hormones), antibacterial peptides, and immune peptides. These small peptides have been confirmed by more and more studies to have important biological significance. Peptidomics is a discipline that studies the structure, function, change rules and related relationships of peptide groups. Peptidomics is a supplement to proteomics. Peptomics can search for peptide markers with biological significance and screen potential therapeutic drugs with biological activity.
The concept of proteome was first proposed by Australian scholars in 1995. It is derived from the hybridization of the two words protein and genome, which refers to a specific time and space. Genome, all the proteins expressed by a cell tissue or an organism. The study of proteomics is called proteomics, which is mainly to study the composition and activity of proteins in cells at the overall level. The specific research content of proteomics includes: protein qualitative and quantitative analysis, protein post-translational modification research, protein structure research, protein function research, small molecule-protein and protein-protein interaction research, etc. Quantitative analysis is divided into non-labeled quantification (label free) and labeled quantification (SILAC, iTraq, TMT, etc.).