Phenols Active Compounds Library Probe+
Phenols Active Compounds Library Probe+
Product Name Cat. No. Compounds Size (10 mM in Pre-dissolved in DMSO )
Phenols Compound Screening Library Probe+ LA-001 Active Compounds 265 
M Series 472
C Series  623
96-well plates
10 μL/well, 20 μL/well,  or 100 μL/well

  The library currently includes 265 phenolic natural products, covering most of the phenolic natural products on the market for drug screening, and the number of M+C series after derivatization and modification has reached ~1100. The library is still increasing, providing a new screening tool for drug screening.
  Phenolic compounds mainly refer to a kind of natural compounds that are formed by direct combination of hydroxyl (-OH) or methoxy (-OMe) with aromatic hydrocarbon groups, which have strong antioxidant, antibacterial, enzyme, and anti-tumor properties. product.

Figure 1 Phenolic active compounds known related diseases





Table 2 Examples of known drug targets for phenolic active compounds



Microtubule-associated protein tau Cytochrome P450 1B1/19A1 Aldo-keto reductase family 1 member B15/B10 (by homology) Xanthine dehydrogenase
Carbonic anhydrase Estrogen receptor Nitric oxide synthase Tyrosyl-DNA phosphodiesterase 1
Arachidonate 5-lipoxygenase Aldose reductase (by homology) Epidermal growth factor receptor erbB1 Cyclooxygenase 2
Cannabinoid receptor 2 Adenosine A1 receptor (by homology) Quinone reductase 2 Dual specificity mitogen-activated protein kinase 1
P-glycoprotein 1 Multidrug resistance-associated protein 1 5-hydroxytryptamine receptor 1A/1B Epidermis-type lipoxygenase 3 (by homology)
D(2) dopamine DNA polymerase alpha catalytic subunit NAD(P)H dehydrogenase [quinone] 1 (by homology) Ribosyldihydronicotinamide dehydrogenase [quinone]
Melatonin receptor type 1A/1B Melatonin-related receptor (by homology) Dual specificity tyrosine-phosphorylation-regulated kinase 1A (by homology) Prostaglandin G/H synthase 1/2
Quinone oxidoreductase (by homology) ATP-binding cassette sub-family G member 2 Caspase-3 subunit p12 Caspase-7 subunit p20 (by homology)
Caspase-6 subunit p18 (by homology) Sodium/myo-inositol cotransporter (by homology) Sodium/glucose cotransporter 4/5 Mitochondrial
Plasmin light chain B Apolipoprotein(a) (by homology) Prostaglandin G/H synthase 1/2 (by homology) Serine/threonine-protein kinase/endoribonuclease IRE1
Beta amyloid A4 protein; ATP-binding cassette sub-family G member 2 Cyclooxygenase 1 Sodium/glucose cotransporter 1/2 Aldehyde dehydrogenase
Solute carrier family 28 member 3 Arachidonate 15-lipoxygenase B Interleukin-2 Low affinity sodium-glucose cotransporter
Inosine-5'-monophosphate dehydrogenase Cell division control protein 42 homolog Ras-related C3 botulinum toxin substrate 1 Epoxide hydratase
Adenosine A3 receptor Phosphodiesterase 5A Neutrophil elastase Azurocidin (by homology)
Green: the same target as the original natural product; black: new target